Is Euxyl K400 patch testing useful in the general population?

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Is Euxyl K400 patch testing useful in the general population?

To the editor: Euxyl K400 (Schulke & Mayr GmbH Co., Norderstedt, German) is added as preservative to cosmetics and industrial products for its antimicrobial activity. It has 2 active components: methyldibromo glutaronitrile, and 2-phenoxi-ethanol. Recently sensitizations to this product has been reported [1, 2], most of them in an occupational setting, leading to its inclusion in some commercia...

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[Will methyldibromo glutaronitrile (Euxyl K400) be the contact allergen of the year 2005 in Navarra?].

Correspondencia Marcos Hervella Garcés Avenida Pío XII, 37-5 B 31008 Pamplona Tfno: 948 273434 E-mail: [email protected] El metildibromoglutaronitrilo es uno de los dos ingredientes activos del Euxyl® K400 y su principal fuente de sensibilización alérgica. También se conoce con el nombre de 1,2-dibromo-2,4-dicianobutano y es una sustancia antimicrobiana de amplio espectro que se emp...

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[Contact sensitization to Euxyl K-400].

INTRODUCTION Euxyl K400 is a widely used preservative in cosmetics, topical drugs, cutting fluids, etc. This antimicrobial product has two active components: methyldibromoglutaronitrile (MDGN), also known as 1,2-dibromo-2,4-dicyanobutane, and 2-phenoxyethanol, in a proportion of 1 to 4. The aim of this study was to assess the prevalence of sensitization to this preservative in cases in our derm...

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Is thrombophilia testing useful?

Thrombophilia is found in many patients presenting with venous thromboembolism (VTE). However, whether the results of such tests help in the clinical management of such patients has not been determined. Thrombophilia testing in asymptomatic relatives may be useful in families with antithrombin, protein C, or protein S deficiency or homozygosity for factor V Leiden, but is limited to women who i...

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Is pharmacogenetic CYP2D6 testing useful?

BACKGROUND Pharmacogenetic testing is used to uncover genetic causes for variations in drug response. Documentation of the method's usefulness in a clinical setting is scarce. The aim of the study was to systematically categorize the experience from routine CYP2D6 genotyping in a diagnostic laboratory. MATERIAL AND METHODS All samples submitted to our laboratory for CYP2D6 genotyping in the p...

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ژورنال

عنوان ژورنال: Asia Pacific Allergy

سال: 2017

ISSN: 2233-8276,2233-8268

DOI: 10.5415/apallergy.2017.7.3.171